SoftGenetics GeneMarker 3.0

SoftGenetics GeneMarker 3.0

Key Features & Capabilities

• Automated Fragment Sizing & Genotyping: Advanced algorithms for precise base pair sizing of DNA fragments and automated allele calling for STR, microsatellite, and SNP markers with customizable panels and binsets.
• Forensic STR Analysis: Compliant modules for forensic human identification, supporting CODIS and other international STR panels, mixture deconvolution, and generating expert system-compatible files.
• Microbial & Microsatellite Analysis: Tools for microbial strain typing (MLVA), plant/animal genotyping, and allele binning for population studies.
• Comparative Genomic Hybridization (aCGH): Specialized module for analyzing array CGH data to detect copy number variations (CNVs), amplifications, and deletions associated with genetic disorders and cancer.
• Loss of Heterozygosity (LOH) & MSI: Capabilities to detect LOH events and Microsatellite Instability (MSI) in paired tumor/normal samples.
• · Batch Processing & Reporting: High-throughput batch analysis of hundreds of samples with customizable report generation for research and compliance purposes.

 What’s New in Version 3.0

• Completely Modernized 64-bit Architecture: Full native 64-bit support, enabling faster processing and handling of much larger datasets (e.g., high-density microarrays, massive batch runs) without memory constraints.
• Redesigned User Interface: A contemporary, tab-based interface with improved workflow navigation, project management, and visualization tools.
• Enhanced Forensic & NGS Integration: Improved tools for analyzing complex forensic mixtures and new modules for analyzing data from Next-Generation Sequencing (NGS)-based STR and SNP panels.
• Expanded Data Import/Export: Support for a wider range of instrument file formats and direct export to more third-party databases and analysis tools.
• Advanced Visualization & QC: New graphing options, quality metric dashboards, and improved manual editing tools for expert review.

💻 System Requirements

• OS: 64-bit Windows 10 or 11.
• CPU: Multi-core Intel i5/i7 or equivalent (higher speed recommended for large batches).
• RAM: 8 GB minimum (16 GB+ highly recommended, especially for aCGH or large NGS data).
• Storage: 1 GB free space for installation.